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Saudi Med J ; 42(3): 299-305, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1106579

ABSTRACT

OBJECTIVES: To identify clinical and laboratory characteristics of the Saudi children with confirmed COVID-19. METHODS: Eighty-eight children (0-14 years) with COVID-19 who were admitted to Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia from April to June 2020 were recruited. RESULTS: Mean age was 5.74 ± 4.7 years with 41 (49.4%) males and 42 (50.6%) females. The length of hospital stay (LOS) ranged from 1 to 17 days. The main source of infection was infected family members. Mean values of C-reactive protein (CRP), serum ferritin, and lactate dehydrogenase (LDH) were noticeably above normal. Degree of severity and length of stay was significantly correlated with lymphopenia (r= -0.36; p=0.001), whereas it was positively correlated with absolute neutrophil count and with high inflammatory markers, such as CRP, LDH, and others. CONCLUSIONS: Identifying the clinical and laboratory characteristics of the Saudi children with confirmed COVID-19 will improve understanding of this disease's presentation and will help put rapid and proper management strategies into place to face this pandemic. A high index of suspicion is needed for cases presenting with multi-system inflammatory disease, which represented 5.7% of the included study population.


Subject(s)
COVID-19/diagnosis , Systemic Inflammatory Response Syndrome/diagnosis , Adolescent , Asymptomatic Infections , Biomarkers/blood , C-Reactive Protein/metabolism , COVID-19/complications , COVID-19/epidemiology , COVID-19/therapy , Child , Child, Preschool , Female , Ferritins/blood , Humans , Infant , Infant, Newborn , L-Lactate Dehydrogenase/blood , Length of Stay , Lymphopenia/complications , Male , Pandemics , Retrospective Studies , SARS-CoV-2 , Saudi Arabia/epidemiology , Severity of Illness Index , Systemic Inflammatory Response Syndrome/complications , Systemic Inflammatory Response Syndrome/epidemiology , Systemic Inflammatory Response Syndrome/therapy
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